Acute Inflammation
Acute inflammation is created using carragenan induced rat paw edema. Several compounds have been screened for last many years at Raj Biotech using this model.
Subacute inflammation
Cotton pellet granuloma, air pouch granuloma model is frequently used at our place to screen compounds for their sub acute anti-inflammatory activity
Chronic inflammation
FCA model of chronic inflammation is being used as a model for screening compounds with chronic anti-inflammatory activity. MAny parameters like IL2, IL6, CRP, PGE are screened.
Analgesics
Peripheral Analgesic Activity
Acetic acid writhing model is used to screen peripheral analgesic activity. It is routinely used at Raj Biotech to screen compounds.
Central Analgesic Activity
Tail immersion test and hot plate thermal hyperalgesia are undertaken regularly for screening this activity. Opoids or central analgesics are banned for usage, making this test very important and unique.
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